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5-Chloro-2-thiophenecarboxylic acid

2-chlorothiophene-5-carboxylic acid is a yellow to brown solid with a unique sulfur odor. It is only

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Contenuto

2-chlorothiophene-5-carboxylic acid is a yellow to brown solid with a unique sulfur odor. It is only slightly soluble in water at room temperature, but can dissolve in organic solvents.

Scopo:

2-chlorothiophene-5-carboxylic acid is often used as an intermediate in organic synthesis, especially in the preparation of thiophene compounds, which has important application value. It can also be used as a dye, photosensitizer, fluorescent analysis reagent, etc.

Metodo di fabbricazione:

There are many methods for preparing 2-chlorothiophene-5-carboxylic acid, and one common method is to react 2-chlorothiophene with methanol in the presence of sodium hydroxide to produce 2-chlorothiophene-5-methanol. Then, under the action of an acid catalyst, the methanol group is converted to a carboxyl group to obtain 2-chlorothiophene-5-methyl acid.

Informazioni sulla sicurezza:

2-chlorothiophene-5-carboxylic acid is irritating and should be avoided from contact with skin, eyes, and mucous membranes. During operation, personal protective equipment such as chemical protective gloves, glasses, and face shields should be worn to ensure sufficient ventilation conditions. Attention should be paid to avoiding contact with strong oxidants and acidic substances to prevent accidental reactions. During storage and transportation, it is necessary to avoid high temperatures and sources of fire.

Nome5-Chloro-2-thiophenecarboxylic acid
SinonimiAKOS B000092
Rivaroxaban Impurity N
Chlorothiophene-2-carboxy
2-Chlorothiophene-5-formicacid
5-chlorothiophene-2-carboxylate
5-chloro-2-thiophenecarboxylicaci
5-CHLORO-2-THIOPHENECARBOXYLIC ACID
2-chlorothiophene-5-carboxylic acid
5-Chloro-2-thiophenecarboxylic acid
5-Chlorothiophene-2-carboxylic acid
5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID
5-Chlorothiophene-2-carboxilic acid
5-Chloro-2-thiophene carboxylic acid
2-Thiophenecarboxylic acid, 5-chloro-
CAS24065-33-6
EINECS000-000-0
InChIInChI=1/C5H3ClO2S/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H,7,8)/p-1
InChIKeyQZLSBOVWPHXCLT-UHFFFAOYSA-N
Formula molecolareC5H3ClO2S
massa molare162.59
Densità1.466 (estimate)
Punto di fusione154-158°C(lit.)
punto Boling287.0±20.0 °C(Predicted)
Punto Flash127.4°C
SolubilitàDMSO (leggermente), metanolo (leggermente)
Pressione del vapore0.00119mmHg at 25°C
AspettoWhite solid
ColoreCream-yellow
BRN118361
pKa3.32±0.10(Predicted)
Condizioni di conservazioneMantenere in luogo buio, sigillato in asciutto, temperatura ambiente

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