DBCO-PEG-SH (dibenzocicloctine-polietilenglicole-tiolo) - Focus sui derivati PEG

DBCO-PEG-SH (dibenzocyclooctyne-polyethylene glycol-thiol) undergoes chemical reactions without any metal catalysts.

The strain-promoted 1,3-dipolar cycloaddition of cyclooctyne and azide, also known as the copper-free click reaction, is a bioorthogonal reaction that allows the conjugation of two molecules in aqueous solution.

DBCO-PEG derivatives exhibit fast kinetics and stability in aqueous buffers.

DBCO reagents can be used to label azide-modified biomolecules without the need for toxic copper catalysts.

PEGylation can increase the solubility and stability of peptides and proteins and reduce their immunogenicity.

It can also inhibit the nonspecific binding of charged molecules to the modified surface.

English name: DBCO-PEG-SH

Alias:

Dibenzocycolctyne-PEG-Thiol

DBCO-PEG-Thiol

Molecular weight: 400, 500, 600, 1k, 2k, 3.4k, 5k (customizable)

Purezza del prodotto:

≥95%

Uso del prodotto:

Applicato nella ricerca medica, rilascio di farmaci, nanotecnologia e ricerca di nuovi materiali, cultura cellulare. E la ricerca dei ligandi, il sostegno alla sintesi dei peptidi, i composti polimerici innestati, i nuovi materiali e i rivestimenti funzionali modificati del polietilenglicolo e altri composti attivi.