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L-istidina diidrocloruro

L-histidine dihydrochloride - Names and IdentifiersNameL-histidine dihydrochlorideSynonymsCCRIS

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L-histidine dihydrochloride - Names and Identifiers

NomeL-istidina diidrocloruro
SinonimiCCRIS 7814
H-His-OH.xHCl
Crystalline2HCl
histidine hydrochloride
L-Histidine hydrochloride
L-HISTIDINE DIHYDROCHLORIDE
L-istidina diidrocloruro
L-histidine monohydrochloride
L-Histidine hydrochloride solution
1-carboxy-2-(1H-imidazol-5-yl)ethanaminium chloride
2-{[4-(1-methylethyl)phenyl]methylidene}-3-oxo-2,3-dihydro-1-benzofuran-6-yl cyclohexanecarboxylate
CAS1007-42-7
645-35-2
7048-02-4
EINECS213-754-2
InChIInChI=1/C6H9N3O2.ClH/c7-5(6(10)11)1-4-2-8-3-9-4;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H

L-histidine dihydrochloride - Physico-chemical Properties

Formula molecolareC6H10ClN3O2
massa molare191.62
Punto di fusione240-245°C (dec.)
punto Boling458.9°C at 760 mmHg
Specific Rotation(α)[α]D20 +7.0~+10.0°(c=2,HCl)
Punto Flash231.3°C
SolubilitàEasily soluble in formic acid, soluble in water, insoluble in ethanol and B
Pressione del vapore3.25E-09mmHg at 25°C
AspettoWhite crystal or crystalline powder
Condizioni di conservazioneAtmosfera inerte, temperatura ambiente
MDLMFCD00064556
Proprietà fisiche e chimicheWhite crystalline substance; Soluble in water, acidic aqueous solution, insoluble in ethanol, ether and chloroform; Decomposition point of 245 ℃; specific rotation [α]20D 47.6 °(0.5-2 mg/mL in H2O);[α]25D 8.5 °(0.5-2 mg/mL, 6 mol/L HCl).
UtilizzoFor biochemical research, medicine used for the treatment of anemia and angina, aortitis, heart failure and other cardiovascular diseases, can also be used for the auxiliary treatment of peptic ulcer. Used as pharmaceutical raw materials and food additives

L-histidine dihydrochloride - Risk and Safety

Descrizione della sicurezzaS22 - Do not breathe dust.
S24/25 Evitare il contatto con la pelle e gli occhi.
ID delle Nazioni UniteUN 1789 8/PG 3
WGK Germania3
FLUKA MARCA F CODICI3-10

L-histidine dihydrochloride - Reference

Reference 1. [IF=3.398] Hao Zhang et al."α-Glucosidase-Mediated Glucometer Readout for Portable Monitoring of Acarbose and Migliol."Chemosensors. 2022 Jun;10(6):198

L-histidine dihydrochloride - Reference Information

traits white crystalline substance
properties white crystalline substance; Soluble in water, acidic in aqueous solution, insoluble in ethanol, ether and chloroform; The decomposition point is 245 ℃; The specific rotation [α]20D 47.6 (0.5-2 mg/ml,H2O);[α]25D 8.5 (0.5-2 mg/ml,6 mol/L HCl).
uses the main components of amino acid drugs, amino acid infusion and comprehensive amino acid preparations; It is used for adjuvant treatment of peptic ulcer. Anemia, aortitis, cardiac insufficiency and other cardiovascular diseases; nutritional supplements, the synthesis speed in the human body is slow, quasi-essential amino acids, can be used to strengthen infant food, after surgery patient food.
Used in biochemical research, used in medicine to treat anemia and angina pectoris, aortitis, cardiac insufficiency and other cardiovascular diseases, and can also be used for adjuvant treatment of peptic ulcers. Used as pharmaceutical raw materials and food additives
metodo di produzione hemoglobin is used as raw material, hydrolyzed with hydrochloric acid, separated by column chromatography with ion exchange resin, and then recrystallized with hydrochloric acid.

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