ESTERE TERT-BUTIL (S)-2-TIOCARBAMOIL-PIRROLIDINA-1-ACIDO CARBOSSILICO

(S)-2-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Names and Identifiers

Nome	ESTERE TERT-BUTIL (S)-2-TIOCARBAMOIL-PIRROLIDINA-1-ACIDO CARBOSSILICO
Sinonimi	1-Pyrrolidineca TERT-BUTYL2(S)-THIOCARBAMOYLPYRROLIDINE-1-CARBOXYLATE tert-butyl (S)-2-carbamothioylpyrrolidine-1-carboxylate (S)-tert-butyl 2-thiocarbaMoylpyrrolidine-1-carboxylate 2R-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-2-Thiocarbamoylpyrrolidine-1-carboxylic acid tert-butyl este ESTERE TERT-BUTIL (S)-2-TIOCARBAMOIL-PIRROLIDINA-1-ACIDO CARBOSSILICO 1-Pyrrolidinecarboxylic acid, 2-(aMinothioxoMethyl)-, 1,1-diMethylethyl ester, (2S)-
CAS	101410-18-8

(S)-2-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Physico-chemical Properties

Formula molecolare	C10H18N2O2S
massa molare	230.33
Densità	1.191±0.06 g/cm3(Predicted)
Punto di fusione	195-199 °C(Solv: tetrahydrofuran (109-99-9))
punto Boling	339.5±52.0 °C(Predicted)
pKa	12.98±0.20(Predicted)
Condizioni di conservazione	2-8°C

(S)-2-THIOCARBAMOYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Introduction

N-BOC-thio-L-prolinamide is an organic compound with the following properties:

1. appearance: generally white crystalline or crystalline powder objects.
2. molecular formula: C13H22N2O4S.
3. Molecular weight: 298.39g/mol.
4. melting point: about 182-185 ℃.

N-BOC-thio-L-prolinamide is mainly used as a protecting group (protecting group), usually in the synthesis of peptides or proteins, the amino group of leucine is protected to prevent side reactions in the reaction process. In addition, it can also be used in other organic synthesis reactions.

The preparation of N-BOC-thio-L-prolinamide is usually completed by the following steps:

1. thio-L-prolinamide is reacted with Boc2O (samarium tert-butoxycarbonyl chloride) in an appropriate solvent.
2. After the reaction is completed, the protecting group is usually removed from the product using acidic conditions (such as acetic acid).

Safety precautions when using or handling N-BOC-thio-L-prolinamide:

1. Avoid inhalation, contact with skin or ingestion of the compound. Appropriate protective measures, such as protective gloves, goggles and laboratory external air devices, should be worn.
2. in the operation to avoid contact with strong oxidants and acidic substances, to prevent dangerous reaction.
3. Experiments should be conducted in a well-ventilated environment and follow relevant safety operating procedures.
4. Waste treatment should be carried out in accordance with local chemical waste treatment regulations to avoid environmental pollution.

Please note that before using any chemical, it is important to understand its nature, use and safety information in detail, and to follow appropriate laboratory conditions and procedures.